Qualitative understanding of partition preferences

Introduction
Cavity model
Rules for partitioning ...
     ...of a given compound
           Recall information ...
           Case Ia
           Case Ib
           Case Ic
           Case IIa
           Case IIb
           Other cases
           Overview
           Furter information
     ...of various compounds
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The cavity model in quantitative terms

Selftest
Problems
Intermolecular interactions in every day life
FAQ

Case IIa

Furthermore we can expect that :

Rule 2:
The partitioning of an apolar molecule into various bipolar phases will decrease with the number-density and strength of H-bonds in these phases. This explains what is behind the frequently used term hydrophobicity . The examples below show how drastic this effect is.

 

solvent
Ksolvent / air of octane
n-heptane
C7H16
8578

Partitioning decreases
with increasing cohesive
energy in the solvents

diethyl ether
H5C2-O-C2H5
8287
1-butanol
C4H9-OH
2264
1,3-propanediol
C3H6-(OH)2
79
1,2-ethanediol
C2H4-(OH)2
13
water
H-O-H
0.008

 

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