Sample preparation

Sample preparation - context
Sample preparation - motivation
Purpose of sample preparation
     Interferents in the sample ...
     LOD and LOQ
Overview of preparation methods
     Liquid liquid extraction (LLE)
     Solid phase extraction (SPE)
     Solid phase microextraction (SPME)
     Purge and trap (PT)
     (Accelerated) Solvent extraction ((A)SE)
     Supercritical fluid extraction (SFE)
      Filter Techniques (FT)
Box 10 Filtration
Box 11 Sorbents
Box 12 Preconcentration
Self test
Problems
End of chapter

Limit of detection (LOD)

The lowest possible analyte concentration that can be reliably detected using a specific analytical method (note that the corresponding signal is too low to allow reliable analyte quantification). Most commonly, the LOD is defined relative to the background noise of the detector (see Chapter XI.5.5 in the script). The higher the background signal and its noise, the higher LOD.

 

Limit of quantitation (LOQ)

The lowest possible analyte concentration that can be reliably quantified using a specific analytical method. Most commonly, the LOQ is defined relative to the background noise of the detector (see Chapter XI.5.5 in the script). The higher the background signal and its noise, the higher LOQ.