Sample preparation

Sample preparation - context
Sample preparation - motivation
Purpose of sample preparation
Overview of preparation methods
     Liquid liquid extraction (LLE)
     Solid phase extraction (SPE)
     Solid phase microextraction (SPME)
     Purge and trap (PT)
           General description of PT
           Illustration of PT
           Detailed description of PT
     (Accelerated) Solvent extraction ((A)SE)
     Supercritical fluid extraction (SFE)
      Filter Techniques (FT)
Box 10 Filtration
Box 11 Sorbents
Box 12 Preconcentration
Self test
Problems
End of chapter


General description of Purge and trap

principle:

  1. Purge: phase transfer of analyte(s) with relatively large air/water partition constants from an aqueous phase W into gas bubbles created by purging the sample

    non-volatile interferents remain in water sample

       
  2. Trap: Phase transfer of analyte(s) from purge gas to solid sorbent in a filter unit

    pre-concentration of analyte in the sorbent

  3. Thermal desorption of analyte from the sorbent in an oven connected to the GC column

advantage:

exhaustive extraction of 'volatile' analytes
from water samples

disadvantage:

potential breakthrough of analyte through sorbent filter