Separation of analytes

Separation of analytes - context
Analyte mixtures and separation - 1
Analyte mixtures and separation - 2
Analyte mixtures and separation - 3
Introduction to chromatography
Chromatographic columns
Principle setup of a chromatographic unit
Example of separation
Chromatographic system - 1
Chromatographic system - 2
Standard gas chromatograph
(Old) liquid chromatography unit
(New) liquid chromatography unit
HPLC columns
Comparison GC and HPLC
Selftest
     1) Purpose of chromatographic process
           Answer
     2) Unsuitable compounds
           Answer
     3) HPLC vs. GC
           Answer
     4) Detectors
           Answer
     5) Solvent properties
           Answer
     6) Retention time
           Answer
     7) Analyte identification
           Answer
     8) Irreversible or reversible sorption process
           Answer
     9) Short analysis time
           Answer
     10) Retention factor
           Answer
     11) Breakthrough-curve
           Answer
Problems
End of lesson

2) Unsuitable compounds

 

Question:

Which compounds are not suitable for gas chromatography?

 

Answer:

Large and polar compounds because they (i) sorb too strongly and/or (ii) they may be thermally instable and hence not easily transferred into the gas phase by heating.